Clinical efficacy of <i>Jiawei Shoutai</i> Pills in the treatment of polycystic ovary syndrome with recurrent miscarriage and its impact on pre thrombotic state

WANG Shishuai; YE Liqun; SHAN Lihua; WU Linlin

doi:10.16766/j.cnki.issn.1674-4152.003118

Volume 21 Issue 8

Aug. 2023

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Article Navigation > Chinese Journal of General Practice > 2023 > 21(8): 1339-1342

WANG Shishuai, YE Liqun, SHAN Lihua, WU Linlin. Clinical efficacy of Jiawei Shoutai Pills in the treatment of polycystic ovary syndrome with recurrent miscarriage and its impact on pre thrombotic state[J]. Chinese Journal of General Practice, 2023, 21(8): 1339-1342. doi: 10.16766/j.cnki.issn.1674-4152.003118

Citation:

WANG Shishuai, YE Liqun, SHAN Lihua, WU Linlin. Clinical efficacy of Jiawei Shoutai Pills in the treatment of polycystic ovary syndrome with recurrent miscarriage and its impact on pre thrombotic state[J]. Chinese Journal of General Practice, 2023, 21(8): 1339-1342. doi: 10.16766/j.cnki.issn.1674-4152.003118

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Clinical efficacy of Jiawei Shoutai Pills in the treatment of polycystic ovary syndrome with recurrent miscarriage and its impact on pre thrombotic state

doi: 10.16766/j.cnki.issn.1674-4152.003118

1.
Ningbo Traditional Chinese Medicine Hospital Gynecology, Ningbo, Zhejiang 315010, China

Funds:

2021KY1184

2019A610358

Received Date: 2023-03-29
Available Online: 2023-09-13

Abstract

Abstract

Objective Analyze the clinical efficacy of Jiawei Shoutai Pills in treating patients with polycystic ovary syndrome combined with recurrent miscarriage, and its impact on the patient's pre thrombotic state, providing a basis for clinical treatment. Methods A total of 150 patients with polycystic ovary syndrome and recurrent miscarriage admitted to Ningbo Traditional Chinese Medicine Hospital from July 2019 to June 2021 were selected as the study subjects, They were randomly divided into A team (low molecular weight heparin calcium injection treatment), B team (modified Jiawei Shoutai Pills treatment) and C team (modified Jiawei Shoutai Pills combined with low molecular weight heparin calcium injection treatment), with 50 patients in each team.Compare the TCM syndrome score and endocrine index, coagulation- fibrinolysis index, anticardiolipin antibody. Results After treatment, the C team score of patients was 4.00 (1.46, 8.00) points, lower than the 10.00 (3.75, 11.25) points in the A team and the 11.21 (4.60, 12.18) points in the B team, P < 0.05; C team serum β-human chorionic gonadotropin (β-HCG), progesteroneon (P), estradiol (E₂) were all higher than the B team and A team, P < 0.05; The activated partial thromboplastin time (APTT) and AntithrombinⅢ (ATⅢ) levels in the C team were higher than the traditional Chinese medicine and A team, while fibrinogen (FIB) and d-dimmer (DD) levels were lower than the B team and A team, with P < 0.05; The positive rate of anticardiolipin antibodies in the C team was 10.0% (5/50), which was lower than the LMWH and the Chinese medicine team, all were 28.0% (14/50), P < 0.05. Conclusion Jiawei Shoutai Pills combined with low-molecular-weight heparin calcium injection can effectively improve plasma viscosity, coagulation, fibrinolysis system and uterine artery hemodynamics in patients with polycystic ovary syndrome complicated with recurrent abortion, worthy of clinical application.
- Polycystic ovary syndrome,
- Recurrent abortion,
- Prethrombotic state,
- Jiawei Shoutai Pills,
- Coagulation fibrinolysis

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Clinical efficacy of Jiawei Shoutai Pills in the treatment of polycystic ovary syndrome with recurrent miscarriage and its impact on pre thrombotic state

doi: 10.16766/j.cnki.issn.1674-4152.003118

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