Study on the therapeutic effect of minimally invasive release under microscope combined with postoperative oral administration of Jiangu capsules on cubital tunnel syndrome

GAO Xing; MENG Yufeng; WANG Wei; LI Shiying; ZHANG Tongtong

doi:10.16766/j.cnki.issn.1674-4152.003289

Volume 21 Issue 12

Dec. 2023

Turn off MathJax

Article Contents

Article Navigation > Chinese Journal of General Practice > 2023 > 21(12): 2057-2059

GAO Xing, MENG Yufeng, WANG Wei, LI Shiying, ZHANG Tongtong. Study on the therapeutic effect of minimally invasive release under microscope combined with postoperative oral administration of Jiangu capsules on cubital tunnel syndrome[J]. Chinese Journal of General Practice, 2023, 21(12): 2057-2059. doi: 10.16766/j.cnki.issn.1674-4152.003289

Citation:

GAO Xing, MENG Yufeng, WANG Wei, LI Shiying, ZHANG Tongtong. Study on the therapeutic effect of minimally invasive release under microscope combined with postoperative oral administration of Jiangu capsules on cubital tunnel syndrome[J]. Chinese Journal of General Practice, 2023, 21(12): 2057-2059. doi: 10.16766/j.cnki.issn.1674-4152.003289

Citation:

GAO Xing, MENG Yufeng, WANG Wei, LI Shiying, ZHANG Tongtong. Study on the therapeutic effect of minimally invasive release under microscope combined with postoperative oral administration of Jiangu capsules on cubital tunnel syndrome[J]. Chinese Journal of General Practice, 2023, 21(12): 2057-2059. doi: 10.16766/j.cnki.issn.1674-4152.003289

PDF( 433 KB)

Study on the therapeutic effect of minimally invasive release under microscope combined with postoperative oral administration of Jiangu capsules on cubital tunnel syndrome

doi: 10.16766/j.cnki.issn.1674-4152.003289

GAO Xing^{1, 2
,
,}
, MENG Yufeng^{1, 2}
, WANG Wei^{1, 2}
, LI Shiying^{1, 2}
, ZHANG Tongtong^{1, 2}

1.
2nd Hand & Microsurgery of Cangzhou Hospital of Integrated TCM-WM·Hebei, Cangzhou, Hebei 061001, China

Funds:

2021299

Received Date: 2023-07-31

Abstract

Abstract

Objective To investigate the application effect of oral Jiangu capsules in minimally invasive release of elbow tunnel syndrome patients under microscope, It aims to provide reference for research on the treatment of the disease. Methods A total of 94 patients with cubital tunnel syndrome from January 2022 to April 2023 were selected as study subjects, and randomly divided into two groups of 47 patients each. Both groups underwent anterior ulnar nerve surgery, while the control group underwent minimally invasive release surgery under a microscope. The observation group received postoperative oral treatment with Jiangu capsules. Both groups completed 4 weeks of treatment, and efficacy, ulnar nerve conduction velocity, latency, amplitude, interleukin-1 (IL-1), nerve growth factor (NGF), motor function, sensory function and visual analogue scale (VAS) scores were compared between the two groups. Results The efficacy rate of the observation group after 4 weeks of intervention was 95.74% (45/47), which was higher than that of the control group [82.98% (39/47), χ²=4.029, P=0.045]; after 4 weeks of intervention, ulnar nerve conduction velocity, amplitude and NGF levels were higher in the observation group than in the control group (all P < 0.05). The incubation period and IL-1 levels were lower than in the control group (all P < 0.05). After 4 weeks of intervention, motor and sensory functions were improved in both groups, and pain was relieved. The grip strength of the index finger [(3.73±0.56) kg vs. (2.85±0.45) kg] and middle finger [(5.78±0.94) kg vs. (4.64±0.87) kg] in the observation group was higher than in the control group (both P < 0.05). DASH [(26.95±4.19) points vs. (36.39±5.51) points] and VAS [(1.03±0.43) points vs. (3.26±0.52) points] scores were lower than in the control group (both P < 0.05). Conclusion Minimally invasive microscopic release combined with postoperative oral administration of Jiangu Capsule can improve the efficacy rate of patients with cubital tunnel syndrome, help improve ulnar nerve conduction velocity, IL-1 and NGF levels, improve motor and sensory functions, and alleviate pain in patients. It is worth promoting and using.
- Microscopic minimally invasive release combined surgery,
- Jiangu Capsules,
- Elbow tunnel syndrome,
- Therapeutic effect,
- Interleukin-1,
- Nerve growth factor

FullText(HTML)

References(20)

References

[1]	宿晓雷, 余航, 李闯, 等. 中医疗法结合3D打印技术治疗中重度肘管综合征[J]. 中国中西医结合外科杂志, 2021, 27(3): 498-502. doi: 10.3969/j.issn.1007-6948.2021.03.024 SU X L, YU H, LI C. Treatment of moderate-severe cubital tunnel syndrome with integrated traditional Chinese and Western medicine therapy combined with 3D printing technology[J]. Chinese Journal of Surgery of Integrated Traditional and Western Medicine, 2021, 27(3): 498-502. doi: 10.3969/j.issn.1007-6948.2021.03.024
[2]	户文耀, 李汶霖, 王洋, 等. WALANT麻醉联合小切口原位松解术治疗肘管综合征的疗效分析[J]. 中国骨与关节损伤杂志, 2021, 36(3): 294-296. HU W Y, LI W L, WANG Y, et al. Analysis of the efficacy of WALANT anesthesia combined with small incision in situ release surgery in the treatment of cubital tunnel syndrome[J]. Chinese Journal of Bone and Joint Injury, 2021, 36(3): 294-296.
[3]	DE RUITER G C W, DE JONGE J G H, VLAK M H M, et al. Letter to the editor regarding "Ulnar Neuropathy Caused by a Muscular Arcade of Struthers"[J]. World Neurosurg, 2021, 148: 228-229. doi: 10.1016/j.wneu.2021.01.073
[4]	李海滨, 王铭, 代娟, 等. 半开放手术松解治疗肘管综合征合并肘关节骨性关节炎35例[J]. 中国微创外科杂志, 2022, 28(11): 888-892. doi: 10.3969/j.issn.1009-6604.2022.11.009 LI H B, WANG M, DAI J, et al. Semi-open surgical release in the treatment of cubital tunnel syndrome combined with elbow osteoarthritis: report of 35 cases[J]. Chinese Journal of Minimally Invasive Surgery, 2022, 28(11): 888-892. doi: 10.3969/j.issn.1009-6604.2022.11.009
[5]	涂振兴, 王斌, 张顶顶, 等. 显微镜下神经松解治疗非创伤性Ⅱ型Guyon管综合征[J]. 实用骨科杂志, 2022, 28(2): 166-169. TU Z X, WANG B, ZHANG D D, et al. Neurolysis under a microscope for the treatment of non traumatic type Ⅱ Guyon' s tunnel syndrome[J]. Journal of Practical Orthopaedics, 2022, 28(2): 166-169.
[6]	RUSSO N, QAYYUM F, DIVANYAN T, et al. Protocol-based treatment of neurogenic thoracic outlet syndrome[J]. J Vasc Surg, 2021, 73(3): 40-41.
[7]	张宪男, 顾宇, 张梁, 等. 尺神经松解前置合并示指外展功能重建治疗重度肘管综合征20例[J]. 中国中医骨伤科杂志, 2022, 30(5): 73-76. ZHANG X N, GU Y, ZHANG L, et al. 20 cases on anterior ulnar nerve release combined with reconstruction of finger abduction on the treatment of severe cubital tunnel syndrome[J]. Chinese Journal of Traditional Medical Traumatology & Orthopedics, 2022, 30(5): 73-76.
[8]	焦悦, 刘维, 刘昱材, 等. 金乌骨通胶囊联合塞来昔布胶囊治疗强直性脊柱炎的临床研究[J]. 现代生物医学进展, 2022, 22(5): 852-856. JIAO Y, LIU W, LIU Y C, et al. Clinical study of Jinwugutong Capsule combined with celecoxib capsule in the treatment of ankylosing spondylitis[J]. Progress in Modern Biomedicine, 2022, 22(5): 852-856.
[9]	王立, 谢晴, 吕莉, 等. 旋前方肌肌支移位治疗重度肘管综合征[J]. 中华手外科杂志, 2022, 38(6): 483-486. doi: 10.3760/cma.j.cn311653-20211115-0033 WANG L, XIE Q, LYU L, et al. Motor branch of pronator quadratus transfer for treatment of severe cubital tunnel syndrome[J]. Chinese Journal of Hand Surgery, 2022, 38(6): 483-486. doi: 10.3760/cma.j.cn311653-20211115-0033
[10]	HOSSEINI-FARID M, SCHRIER V J M M, STARLINGER J, et al. Carpal tunnel syndrome treatment and the subsequent alterations in tendon and connective tissue dynamics[J]. Clin Biomech (Bristol, Avon), 2021, 88: 105440. DOI: 10.1016/j.clinbiomech.2021.105440.
[11]	李阳, 谢康, 袁毅, 等. 造影下克氏针撬拨复位弹性髓内钉固定治疗低龄儿童Judet Ⅳ型桡骨颈骨折效果观察[J]. 中华全科医学, 2021, 19(9): 1459-1462. doi: 10.16766/j.cnki.issn.1674-4152.002085 LI Y, XIE K, YUAN Y, et al. Treatment of JudetⅣtype radial neck fracture in young children with Kirschner wire percutaneous leverage reduction and elastic intramedullary nail fixation under elbow arthrography[J]. Chinese Journal of General Practice, 2021, 19(9): 1459-1462. doi: 10.16766/j.cnki.issn.1674-4152.002085
[12]	王瀚博, 刘瑞, 赵建民, 等. 肌骨超声结合神经电生理检查对肘管综合征术前的指导意义[J]. 内蒙古医科大学学报, 2021, 43(5): 485-488. WANG H B, LIU R, ZHAO J M, et al. The guiding significance of muscle bone ultrasound combined with neuroelectrophysiological examination for preoperative diagnosis of cubital tunnel syndrome[J]. Journal of Inner Mongolia Medical University, 2021, 43(5): 485-488.
[13]	代丽, 余航, 陈华, 等. 针灸结合黄芪桂枝五物汤对保守治疗肘管综合征患者IL-1、NGF和功能恢复的影响[J]. 长春中医药大学学报, 2022, 38(9): 1011-1014. DAI L, YU H, CHEN H, et al. Effects of acupuncture combined with Huangqi Guizhi Wuwu Decoction on IL-1, NGF and functional recovery in patients with the cubital tunnel syndrome treated conservatively[J]. Journal of Changchun University of Chinese Medicine, 2022, 38(9): 1011-1014.
[14]	ZIMMERMAN M, SCHRAMME M, BARTHÉLEMY A, et al. CT is a feasible imaging technique for detecting lesions in horses with elbow lameness: a study of 139 elbows in 99 horses[J]. Vet Radiol Ultrasound, 2022, 63(2): 164-175. doi: 10.1111/vru.13044
[15]	李晓明, 赵云超, 郭东辉, 等. 坚骨胶囊对胫骨高位截骨术后膝关节功能的近期疗效观察[J]. 中国中医骨伤科杂志, 2019, 27(12): 22-25. JLI X M, ZHAO Y C, GUO D H, et al. Observation on short-term efficacy of Jian Gu Capsule on knee function after high tibial osteotomy[J]. Chinese Journal of Traditional Medical Traumatology & Orthopedics, 2019, 27(12): 22-25.
[16]	张磊, 王海林, 刘旋, 等. 尺神经松解前置术治疗肘管综合征的临床疗效及预后的影响因素分析[J]. 局解手术学杂志, 2021, 30(6): 520-524. ZHANG L, WANG H L, LIU X, et al. Clinical efficacy of ulnar nerve release anterior transposition on cubital tunnel syndrome and its influencing factors for prognosis[J]. Journal of Regional Anatomy and Operative Surgery, 2021, 30(6): 520-524.
[17]	薛金雷, 肖海军, 陆义安, 等. 开放腕管松解术与关节镜下腕管松解术治疗腕管综合征的疗效比较[J]. 中国骨与关节损伤杂志, 2021, 36(7): 763-765. XUE J L, XIAO H J, LU Y A, et al. Comparison of therapeutic effects between open carpal tunnel release and arthroscopic carpal tunnel release in the treatment of carpal tunnel syndrome[J]. Chinese Journal of Bone and Joint Injury, 2021, 36(7): 763-765.
[18]	MANZI J E, CICCOTTI M C, TRAUGER N, et al. Increased elbow and olecranon injury history in professional pitchers with increased elbow flexion at ball release[J]. Am J Sports Med, 2022, 50(4): 1054-1060. doi: 10.1177/03635465211072223
[19]	王伟, 李世英, 郭晓平, 等. 坚骨胶囊对肘关节退变性骨关节炎伴尺神经卡压综合征患者术后康复的影响[J]. 中华中医药学刊, 2022, 40(9): 200-203. WANG W, LI S Y, GUO X P, et al. Effect of Jiangu Capsule on postoperative rehabilitation of degenerative osteoarthritis of elbow joint with uinar nerve entrapment syndrome[J]. Chinese Archives of Traditional Chinese Medicine, 2022, 40(9): 200-203.
[20]	武晔, 王晓磊, 郝泽普, 等. 坚骨胶囊佐治类风湿关节炎继发骨质疏松临床评价[J]. 中国药业, 2022, 31(20): 87-90. WU Y, WANG X L, HE Z P, et al. Clinical evaluation of Jiangu Capsules in the adjuvant treatment of osteoporosis secondary to rheumatoid arthritis[J]. China Pharmaceuticals, 2022, 31(20): 87-90.

Relative Articles

Supplements(0)

Cited By

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Tables(3)

Get Citation

PDF

XML

Article Metrics

Article views (175) PDF downloads(8)

Study on the therapeutic effect of minimally invasive release under microscope combined with postoperative oral administration of Jiangu capsules on cubital tunnel syndrome

doi: 10.16766/j.cnki.issn.1674-4152.003289

Abstract

References

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

Study on the therapeutic effect of minimally invasive release under microscope combined with postoperative oral administration of Jiangu capsules on cubital tunnel syndrome

doi: 10.16766/j.cnki.issn.1674-4152.003289

Abstract

References

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

Export File

Citation

Format

Content