Volume 23 Issue 1
Jan.  2025
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XIE Minghui, LIANG Bing, JIN Guoxi, WEI Nana, LIU Yurun. Analysis of factors influencing high risk of type 2 diabetes mellitus combined with malnutrition and sarcopenia in elderly patients[J]. Chinese Journal of General Practice, 2025, 23(1): 65-68. doi: 10.16766/j.cnki.issn.1674-4152.003836
Citation: XIE Minghui, LIANG Bing, JIN Guoxi, WEI Nana, LIU Yurun. Analysis of factors influencing high risk of type 2 diabetes mellitus combined with malnutrition and sarcopenia in elderly patients[J]. Chinese Journal of General Practice, 2025, 23(1): 65-68. doi: 10.16766/j.cnki.issn.1674-4152.003836
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Analysis of factors influencing high risk of type 2 diabetes mellitus combined with malnutrition and sarcopenia in elderly patients

doi: 10.16766/j.cnki.issn.1674-4152.003836
  • 1.

    Department of General Practice, the First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui 233004, China

Funds:

 202204295107020049

 2020byzd168

  • Received Date: 2024-05-27
    Available Online: 2025-02-13
    Abstract
  •   Objective   This study aims to investigate the high risk of sarcopenia in elderly patients with type 2 diabetes mellitus complicated with malnutrition, and analyze underlying causes of sarcopenia.   Methods   A total of 212 elderly patients with type 2 diabetes mellitus and malnutrition (aged≥60 years old) hospitalized at the First Affiliated Hospital of Bengbu Medical University from September 2023 to April 2024 were selected as the research objects. Malnutrition patients were screened using the mini-nutritional assessment short-form (MNA-SF), and calf circumference was measured to calculate the Ishii score. According to the Ishii scores, the patients were divided into the high-risk group (142 cases) and the low-risk group (70 cases), and comparisons were made between the two groups. Multivariate logistic regression was used to analyze the factors influencing the high risk of sarcopenia.   Results   A comparison between the low-risk group and the high-risk group for sarcopenia in elderly patients with type 2 diabetes mellitus complicated with malnutrition revealed 11 statistically significant independent variables. These variables included age (year), BMI, hemoglobin (Hb), prealbumin (PA), 24-hour urinary microalbumin (24hUMA), insulin resistance index (HOMA-IR), insulin injection, sodium-dependent glucose transporters 2 inhibitor (SGLT-2i), and ADL score (P < 0.05). Multivariate logistic regression analysis showed that age 60-69 years, BMI < 21, PA < 280 mg/L, 24hUMA≥30 mg/24 h, HOMR-IR≥2.69, SGLT-2i, ADL < 70, and insulin were risk factors for high risk of sarcopenia, while insulin injection was a protective factor.   Conclusion   Elderly patients with type 2 diabetes mellitus complicated with malnutrition have a high incidence of sarcopenia. General practitioners should intervene promptly to reverse risk factors, control blood glucose, improve nutritional status, delay the occurrence of sarcopenia, and reduce the risk of diabetic complications such as falls and osteoporosis.

     

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