Investigation and analysis of problems related to clinical application of hypoglycemic drugs in diabetic patients

LI Yang; HU Xiaolei; ZHU Yuehao

doi:10.16766/j.cnki.issn.1674-4152.003840

Volume 23 Issue 1

Jan. 2025

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LI Yang, HU Xiaolei, ZHU Yuehao. Investigation and analysis of problems related to clinical application of hypoglycemic drugs in diabetic patients[J]. Chinese Journal of General Practice, 2025, 23(1): 81-84. doi: 10.16766/j.cnki.issn.1674-4152.003840

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LI Yang, HU Xiaolei, ZHU Yuehao. Investigation and analysis of problems related to clinical application of hypoglycemic drugs in diabetic patients[J]. Chinese Journal of General Practice, 2025, 23(1): 81-84. doi: 10.16766/j.cnki.issn.1674-4152.003840

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Investigation and analysis of problems related to clinical application of hypoglycemic drugs in diabetic patients

doi: 10.16766/j.cnki.issn.1674-4152.003840

LI Yang¹
, HU Xiaolei²
, ZHU Yuehao^{1
,
,}

1.
Department of Pharmacy, Bengbu Municipal Second People Hospital, Bengbu, Anhui 233000, China

Funds:

KJ2020ZD53

Received Date: 2024-06-07
Available Online: 2025-02-13

Abstract

Abstract

Objective Based on the Spanish classification (GRANADA-Ⅱ), drug-related problems (DRPs) in the clinical application of hypoglycemic drugs in inpatients with diabetes is investigated and analyzed. Methods A retrospective study was conducted to select 400 hospitalized patients with diabetes admitted to Bengbu Municipal Second People Hospital from January 2023 to December 2023 as the study objects. Drug regimens were evaluated and classified according to the Spanish classification (Granada-Ⅱ). Results A total of 400 hospitalized diabetic patients were included, including 202 males and 198 females, involving a total of 16 departments. Drug regimens for these patients were evaluated and classified according to the Granada-Ⅱ classification. The results showed that there were DRPs occurred in 77 cases (19.25%), including DRP3 (55 cases, 13.75%), DRP5 (50 cases, 12.50%), and DRP6 (23 cases, 5.75%). The total dosage was 150 doses. Among them, the inappropriate usage [65 doses (43.33%)] was the most prominent, followed by over-recommended dose medication [24 doses (16.00%)] and incompatibility[23 doses (15.33%)], combined interaction drugs [20 doses (13.33%)] and the lowest incidence was contraindications [18 doses (12.00%)]. Conclusion There are still some problems in the use of hypoglycemic drugs in patients with diabetes in Bengbu Municipal Second People Hospital, including incompatibility and inappropriate usage, which can be evaluated by Granada-Ⅱ classification. For common DRPs such as drug dose errors and drug interactions, clinical treatment should strengthen patient education, optimize drug treatment plan, and provide individualized medication guidance to reduce the occurrence of DRPs.
- Diabetes,
- Granada-Ⅱ classification,
- Hospitalized patients,
- Hypoglycemic drugs,
- Drug related problems

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References

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Investigation and analysis of problems related to clinical application of hypoglycemic drugs in diabetic patients

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