Analysis clinical characteristics and pathology of colorectal polyps in various age groups

ZHAO Ning; WANG Yuanyuan; JIANG Xia; ZHAO Zengren

doi:10.16766/j.cnki.issn.1674-4152.003448

Volume 22 Issue 4

Apr. 2024

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Article Navigation > Chinese Journal of General Practice > 2024 > 22(4): 555-558

ZHAO Ning, WANG Yuanyuan, JIANG Xia, ZHAO Zengren. Analysis clinical characteristics and pathology of colorectal polyps in various age groups[J]. Chinese Journal of General Practice, 2024, 22(4): 555-558. doi: 10.16766/j.cnki.issn.1674-4152.003448

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ZHAO Ning, WANG Yuanyuan, JIANG Xia, ZHAO Zengren. Analysis clinical characteristics and pathology of colorectal polyps in various age groups[J]. Chinese Journal of General Practice, 2024, 22(4): 555-558. doi: 10.16766/j.cnki.issn.1674-4152.003448

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Analysis clinical characteristics and pathology of colorectal polyps in various age groups

doi: 10.16766/j.cnki.issn.1674-4152.003448

ZHAO Ning¹
, WANG Yuanyuan^{1, 2}
, JIANG Xia^{1, 2}
, ZHAO Zengren^{1, 2
,
,}

1.
Gastrointestinal Disease Center, the First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China

Funds:

82203623

YZ202201

YZ202305

H2020206374

LS202001

Received Date: 2023-12-02
Available Online: 2024-05-29

Abstract

Abstract

Objective This study aims to investigate the characteristics of colorectal polyps in different age populations, providing a clinical foundation for early screening of intestinal tumors. Methods We conducted a retrospective analysis of clinical data from 571 patients with colorectal polyps at the First Hospital of Hebei Medical University, covering the period from April 2022 to March 2023. These patients were divided into three groups based on age: young group (75 patients, ≤44 years old), middle-aged group (256 patients, 45-59 years old), and elderly group (240 patients, ≥60 years old). The biological characteristics of colorectal polyps in each group were analyzed using the Chi-squared test. Results Male patients were more common in the young and middle-aged groups, whereas female patients were more prevalent in the elderly group (P < 0.001). Comparing the three groups, the incidence of polyps in the ascending colon was highest in elderly group (P=0.002), and the incidence of rectal polyps was highest in young group (P=0.001). Notably, the elderly group exhibited a significantly higher incidence of neoplastic rectal polyps compared to the middle-aged and young group [64.7% (139/215) vs. 34.9% (60/172) vs. 21.2% (14/66), P < 0.001]. Additionally, the incidence of multiple polyps, polyps with a size ≥1.0 cm, and tubular adenomas were highest in elderly group (P < 0.05), while there was no significant difference in the lengths among different pathological types of polyps (P>0.05). The incidence of tubular adenomas in polyps with ≤0.5 cm and 0.6-0.9 cm were highest in elderly group (P < 0.001), while the incidence of hyperplastic polyps was lowest in elderly group (P < 0.001). However, there was no significant difference in the pathological types of polyps with a size ≥1.0 cm among the three groups, with tubular adenomas being the most common for this size polyps (P>0.05). Conclusion The biological characteristics of colorectal polyps exhibit variations across different age groups, including changes in the risk population, growth position, size, number, and pathological types, which tend to follow a discernible trend with increasing age.
- Colorectal polyp,
- Age,
- Clinical characteristics,
- Pathological features

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Analysis clinical characteristics and pathology of colorectal polyps in various age groups

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