2021 Vol. 19, No. 8

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Expert Forum
Progress in the application of general practice intervention after mild traumatic brain injury
HE Xiaoman, LIU Yumei, MAO Mintao, ZHAO Zhijie, YANG Xi-tao, ZHENG Ruizhe
2021, 19(8): 1251-1254. doi: 10.16766/j.cnki.issn.1674-4152.002033
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More than 50 million people suffer from traumatic brain injury (TBI) every year in the world, and it is estimated that about half of the population will have one or more TBIs over their lifetime. In all TBI patients, mild traumatic brain injury (mTBI) plays the dominant role, and most of them benefi...
2021, 19(8): 1255-1256.
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Study on risk factors of N-terminal pro-brain natriuretic peptide abnormalities in non-dialysis patients with chronic kidney disease
JIN De-wei, TAO Min, MA Xiao-yan, WANG Yi, SHENG Li-li, LIU Na
2021, 19(8): 1314-1317. doi: 10.16766/j.cnki.issn.1674-4152.002049
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Objective To investigate the risk factors of N-terminal pro-brain natriuretic peptide (NT-proBNP) abnormalities in non-dialysis patients with chronic kidney disease (CKD). Methods Non-dialysis patients hospitalized in the Department of Nephrology from January 1, 2018 to December 31, 2019 at the Shan...
Control study on outpatient Morita therapy and cognitive behavioural therapy in the adjuvant treatment of chronic insomnia
SHI Yu-xin, XIA Zhong, RONG Wei
2021, 19(8): 1318-1321. doi: 10.16766/j.cnki.issn.1674-4152.002050
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Objective To compare the efficacy of outpatient Morita therapy and cognitive behavioural therapy (CBT-I) in the treatment of chronic insomnia and to understand the difference between the two therapies and to promote the clinical application of outpatient Morita therapy. Methods Sixty patients with c...
Comparison of LISA technique and INSURE technique in the treatment of respiratory distress syndrome in premature infants
SONG Fei-fei, ZHANG Lan
2021, 19(8): 1322-1325,1429. doi: 10.16766/j.cnki.issn.1674-4152.002051
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Objective To compare the outcomes and side effects between the less invasive surfactant administration (LISA) and the intubate surfactant extubate (INSURE) method in premature infants with respiratory distress syndrome. Methods In the experimental group, 20 children who met the inclusion criteria we...
Influencing factors analysis of intracranial hemorrhage in premature infants
LIN Yang, MIN Hong, ZHOU Hao-quan, CHEN Ming-wu, PAN Jia-hua
2021, 19(8): 1326-1329. doi: 10.16766/j.cnki.issn.1674-4152.002052
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Objective Intracranial hemorrhage is a common complication in premature infants, which can leave different degrees of neurological sequelae. The purpose of this study was to investigate the high risk factors of intracranial hemorrhage in premature infants and provide theoretical basis for early inte...
Construction and practice of cardiac rehabilitation in the community projects aims at constructing the clinical path of community general practice care under hierarchical medical system
WANG Ying, CHEN Bi-hua, LI Qing, JING Ling, WANG Lin-chuang
2021, 19(8): 1330-1335，1418. doi: 10.16766/j.cnki.issn.1674-4152.002053
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Objective For summary and evaluation of the protype at practice, this research recruited cardiac rehabilitation professionals for in-depth interviews to know the status quo of cardiac rehabilitation service carried out at Longhua community and comb the cardiac rehabilitation in the community to carr...
Analysis on vision and refraction of primary and middle school students in urban rural areas of Shanghai
WANG Yu-lin, XU Qi, HU Die, FU Hua
2021, 19(8): 1336-1338,1342. doi: 10.16766/j.cnki.issn.1674-4152.002054
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Objective To investigate the current situation and epidemiological characteristics of vision and refraction amongst primary and secondary school students in urban rural areas of Shanghai, and to provide reference for the prevention and treatment of myopia amongst primary and secondary school student...
Effect of empowerment education model on patients with poor blood glucose control in diabetes mellitus
HU Xiao-rong, LI Xiu-ying, XU Juan, WU Qing-qing
2021, 19(8): 1339-1342. doi: 10.16766/j.cnki.issn.1674-4152.002055
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Objective To explore the influence of empowerment education mode on self-management ability and blood glucose control level of patients with poor glucose control in diabetes mellitus. Methods Total 90 patients with type 2 diabetes who had poor glucose control were selected from Department of Endocri...
Psychological correlation status and causes of tumour patients at different stages of treatment during the COVID-19 epidemic
HUANG Ze-han, DU Yi-heng, SONG Ya-ting, YAO Huang, YANG Sheng-li, HU Jian-li
2021, 19(8): 1343-1346,1407. doi: 10.16766/j.cnki.issn.1674-4152.002056
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Objective To investigate the psychological state and related causes of tumour patients in different treatment stages during the COVID-19 epidemic. Methods The mental health questionnaire of tumor patients in different stages of the COVID-19 epidemic was designed by self-designed questionnaire, and t...
Clinical application of CT enterography and double-balloon enteroscopy in the diagnosis of suspected small intestinal bleeding
DIAO Lei, HONG Ru-tao, HAN Wei, HU Jing, CHEN Xi
2021, 19(8): 1347-1350. doi: 10.16766/j.cnki.issn.1674-4152.002057
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Objective The clinical data of patients with suspected small bowel bleeding in our hospital were analyzed retrospectively to explore the application value of CT enterography (CTE) and double-balloon enteroscopy (DBE) in the diagnosis of suspected small bowel bleeding. Methods The clinical data of 54...
Application of ultrasound combined with sonohysterography in intrauterine adhesion
SHU Yan, CAI Ting-ting, LIU Ming-song, ZHANG Wei-feng, LU Wen-ming
2021, 19(8): 1351-1353,1366. doi: 10.16766/j.cnki.issn.1674-4152.002058
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Objective With hysteroscopy as the gold standard, the diagnostic sensitivity and grade and type of intrauterine adhesion (IUA) detected by ultrasound combined with sonohysterography (SHG) were analysed, and the application value of ultrasound combined with SHG in detecting IUA was discussed. Methods...
The concept, estimation and application of lung age
LIANG Xiao-lin, XIE Yan-qing, ZHENG Jin-ping, FEI Yue
2021, 19(8): 1354-1357,1361. doi: 10.16766/j.cnki.issn.1674-4152.002059
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Lung age is a term that uses effective age to quantify the physiological function of lung. It was firstly proposed to evaluate the lung function impairment caused by smoking. Estimation of lung age can be derived from the lung age predictive equation based on spirometric indices. The predictive equa...
The clinical application value of homocysteine
LIN Ni, KE Qu-qing, JIANG Ling-yan, OU Lan-zhi, LIU Die-mei, WU Yu-yan, DU Qing-feng
2021, 19(8): 1358-1361. doi: 10.16766/j.cnki.issn.1674-4152.002060
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Homocysteine (Hcy) is produced in the process of essential amino acid methionine to cysteine conversion, and participates in DNA metabolism through methylation. In recent years, many studies have shown that serum Hcy levels were directly or indirectly related to various diseases, such as arterioscle...
The research progress of serum tumor markers in the diagnosis of ovarian cancer
GUO Yu, XU Peng, WANG Bei-di, LI Li-yang, GAO Shuang, KUANG Ye
2021, 19(8): 1362-1366. doi: 10.16766/j.cnki.issn.1674-4152.002061
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Ovarian cancer (OC) is one of the three gynecological malignancies in the world. Due to the lack of obvious clinical symptoms and effective screening methods in early OC, the patients have a high fatality rate, and their prognosis is poor. In recent years, early detection of OC is the hot spot of re...
Clinical study of the effects of threshold pressure load respiratory muscle training on respiratory function rehabilitation in patients with brain trauma
LIU Wei-li, ZHANG Xiao-xiao, LI Fei-xiang, LI Jing-jing, YIN Xian-yin, LI Shu-qiang, LUO Xun, WEN Jun, CUI Jian, WU Rui
2021, 19(8): 1367-1369,1381. doi: 10.16766/j.cnki.issn.1674-4152.002062
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Objective The aim of this study was to observe of the effect of threshold pressure load respiratory muscle training on respiratory function rehabilitation in patients with traumatic brain injury. Methods Sixty patients with brain trauma from March 2018 to June 2019 in the Second Affiliated Hospital ...
Clinical effect of local acupoint selection combined with back transport acupoint embedding in the treatment of dysphagia after stroke
ZHANG Hui-he, CHEN Miao, LI Wei, ZHAO Na, ZHU Zheng-yu
2021, 19(8): 1370-1372,1389. doi: 10.16766/j.cnki.issn.1674-4152.002063
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Objective To explore the clinical effect of local acupoint selection combined with back transport acupoint embedding in the treatment of swallowing disorder after stroke. Methods A total of 96 patients with swallowing disorder after stroke from April 2019 to April 2020 were selected and randomly div...
Exploration and practice of virtual reality technological diagnosis and treatment system in clinical teaching application
LIU Yan-quan, SHEN Jian-zhen, CHEN Qiang, LIU Ting-bo, CHEN Yi, LI Chao, FU Hai-ying
2021, 19(8): 1373-1377. doi: 10.16766/j.cnki.issn.1674-4152.002064
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Objective To analyze and discuss the practical problems and application effects of the diagnosis and treatment platform system of virtual reality (VR) in clinical diagnosis, treatment and teaching, and to provide a new perspective for the reform and development of medical education in my country at ...
Practice and exploration of integration of school and hospital promote reform of training mode for general practitioners of traditional Chinese Medicine
LI Xian-qiang, GUO Li, MA Su-fen, GUO Dong
2021, 19(8): 1378-1381. doi: 10.16766/j.cnki.issn.1674-4152.002065
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The construction of "Integration of school and hospital" is one of the important paths to realize the coordinated development of medical education and research, and it is of great significance for medical colleges and universities to deepen the cooperation of medical education and promote the innova...
Research on the demand of curriculum construction of general practice medicine in undergraduate education
ZHAO Rui, LIU Feng, ZHU Kun, DING Nan-nan
2021, 19(8): 1382-1385. doi: 10.16766/j.cnki.issn.1674-4152.002066
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Objective In order to provide reference for the further promotion of general practice medicine education in colleges and universities, this paper studied the needs of the curriculum construction of general practice medicine in undergraduate education stage. Methods Key event interviews were conducte...
Application effect of flipped teaching mode based on network platform in ultrasonic imaging teaching
LI Liang, ZHOU Wang, ZHANG Chao-xue, WANG Ji-nian
2021, 19(8): 1386-1389. doi: 10.16766/j.cnki.issn.1674-4152.002067
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Objective To explore the application effect of flipped teaching mode based on network platform in the teaching process of ultrasonic medicine during the coronavirus outbreak. Methods Two classes of sophomores selected randomly from the 5 classes majoring medical imaging from March to May 2020, which...
Buffering effect of trait mindfulness on the stress response and negative emotion caused by the new coronary pneumonia epidemic
QIU Xiao-ying, ZHANG Lin-na, CHU Cheng-jing
2021, 19(8): 1390-1394. doi: 10.16766/j.cnki.issn.1674-4152.002068
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Objective This study aimed to investigate the role of trait mindfulness as a buffer against negative emotions and stress responses in community populations during the COVID-19 epidemic. Methods Online questionnaire was used to investigate the demographic data from February 4, 2020 to March 18, 2020 ...
Study on clinical nutrition quality service units via SWOT analysis
YANG Ting-ting, WANG Wen, YANG Yang, GUAN Ke, WANG Wei-xiang, XU Zhen, GAN Yong, SHEN Li-jun
2021, 19(8): 1395-1397. doi: 10.16766/j.cnki.issn.1674-4152.002069
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Objective To explore the application value of clinical nutrition quality service units, hoping to provide guidance for the establishment of efficient and standardised clinical nutrition service modes and accelerating the development of nutrition departments in hospital. Methods With the model of cli...
Analysis of clinical characteristics and risk factors of death in 51 AIDS patients with disseminated Talaromycosis marneffei in Wenzhou
WU Lian-peng, HE Gui-qing, HU Xing-zhong, PAN Yong, TANG Shao-hua
2021, 19(8): 1398-1402. doi: 10.16766/j.cnki.issn.1674-4152.002070
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Objective To understand the clinical characteristics of AIDS patients with disseminated Talaromycosis marneffei in Wenzhou, and to statistically analyze the risk factors of death, so as to provide a basis for clinical diagnosis, treatment and reduction of mortality of patients with these diseases in...
Process management of biological samples in phase Ⅰ clinical trials
ZENG Li-yan, WANG Qian, MENG Xian-min, KE Jing, DONG Hua-juan, LU Hong-zhou
2021, 19(8): 1403-1407. doi: 10.16766/j.cnki.issn.1674-4152.002071
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Objective The quality of biological sample management in phase Ⅰ clinical trials directly affects the authenticity and accuracy of clinical trial results. In recent years, the management of biological samples has become one of the research issues of great concern in China and abroad. This study esta...
Survey on awareness rate and coping strategies of osteoporosis risk factors among community residents in Bengbu area
WANG Tao, ZHANG Song, SUN Juan, MENG Jing-nan, CHEN Lin-jie
2021, 19(8): 1408-1410,1426. doi: 10.16766/j.cnki.issn.1674-4152.002072
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Objective To investigate the awareness status and related risk factors of osteoporosis among the community residents in Bengbu area, and provide theoretical basis and experience for the extensive development of health education in this area and the reduction and prevention of osteoporosis in communi...
The effect of oral lidocaine hydrochloride mucilage combined with sodium phosphate in colonoscopy
CHAI Xian-deng, LI Lun-lan, YANG Gui-fang, LI Yang, SUN Bin
2021, 19(8): 1411-1414,1432. doi: 10.16766/j.cnki.issn.1674-4152.002073
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Objective To explore the application effect of oral lidocaine hydrochloride mucilage combined with sodium phosphate solution in bowel preparation in common colonoscopy and to improve the efficiency and quality of colonoscopy. Methods Total 293 patients who underwent general colonoscopy in our hospit...
Study on the effect of cluster nursing on quality of life of elderly patients with osteoporosis
YU Fang-zhen, WU Xiao-xia, JIANG Xin-hua
2021, 19(8): 1415-1418. doi: 10.16766/j.cnki.issn.1674-4152.002074
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Objective To observe the effect of cluster nursing on elderly patients with osteoporosis. Methods Total 110 elderly patients with osteoporosis in Zhejiang Quhua Hospital from October 2017 to October 2020 were selected as the research objects and randomly divided into control group and study group, w...
Observation on the application effect of continuing care based on WeChat platform in patients with gastrointestinal tumors using PICC
HUANG Xiao-qin, LYU Dong-lai, ZHOU Li-mei
2021, 19(8): 1419-1422. doi: 10.16766/j.cnki.issn.1674-4152.002075
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Objective To explore the application effect of WeChat platform in PICC continuous care for patients with gastrointestinal cancer chemotherapy. Methods The 102 patients with PICC intubation gastrointestinal tumors in our hospital from October 2017 to October 2019 were divided into observation group a...
Application of the concept of rapid rehabilitation surgery in perioperative nursing of knee arthroscopy
MA Man-li, SHU Gui-lin, LIU Jun, HE Ke-wu, DU Yi-bin
2021, 19(8): 1423-1426. doi: 10.16766/j.cnki.issn.1674-4152.002076
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Objective To explore the application effect of rapid rehabilitation concept in perioperative nursing of knee arthroscopic surgery. Methods A total of 66 patients undergoing knee arthroscopic surgery in Hefei BOE Hospital from April 2019 to August 2020 were randomly divided into the observation group...
2021, 19(8): 1427-1429. doi: 10.16766/j.cnki.issn.1674-4152.002077
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2021, 19(8): 1430-1432. doi: 10.16766/j.cnki.issn.1674-4152.002078
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General Practice Research
Effect of myosin light chain regulated by cardiac myosin light chain kinase on cardiac hypertrophy
HE Mingyuan, GE Junfeng, HUANG Ling, WANG Shixiang, YAN Yi
2021, 19(8): 1257-1261, 1402. doi: 10.16766/j.cnki.issn.1674-4152.002034
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Objective To investigate the effect of cardiac myosin light chain kinase (cMLCK) on the pathological cardiac hypertrophy induced by AngⅡ. Methods The cMLCK was purified and the active sites of cMLCK were explored in vitro. Wild type cMLCK (WT cMLCK) and its N-terminal knockout variants (ΔNT-cMLCK) a...
Relationship between fasting triglyceride glucose index and arteriosclerosis in patients with essential hypertension
ZENG Rong, YAN Jiafu, ZHENG Keyang, WANG ZAuoguang, QU Fengxue, MU Yifan, CHENG Wenli
2021, 19(8): 1262-1264, 1286. doi: 10.16766/j.cnki.issn.1674-4152.002035
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Objective To study the ambulatory blood pressure and brachial-ankle pulse wave velocity (ba-PWV) in essential hypertension patients with different fasting triglyceride glucose index (TyG index) groups, and to explore the correlation between TyG index and ba-PWV. Methods This retrospective study sele...
Analysis of risk factors for delayed discharge of patients undergoing day surgery for urinary stones
QIU Ling, LIU Chunxiang, ZHU Wei, ZHONG Wen, ZHEN Yuling, HAO Fengling
2021, 19(8): 1265-1268. doi: 10.16766/j.cnki.issn.1674-4152.002036
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Objective To explore the risk factors delayed discharge of patients undergoing day surgery for urinary stones. Methods The electronic medical records of 749 patients undergoing day surgery for urinary stones in the First Affiliated Hospital of Guangzhou Medical University in 2019 were retrospectivel...
Analysis of influencing factors of pain in patients after oocyte retrieval of in vitro fertilization-embryo transfer
LUO Guiying, WANG Jieyu, WANG Chunyan, SONG Linlin, YUAN Lanlan, CAO Yunxia
2021, 19(8): 1269-1272,1321. doi: 10.16766/j.cnki.issn.1674-4152.002037
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Objective To explore the influencing factors of pain after transvaginal aspiration for oocyte retrieval, and to provide theoretical basis for clinical analgesia intervention. Methods A total of 755 patients who underwent in vitro fertilization-embryo transfer vaginal puncture for oocyte retrieval in...
Comparison of the effect of resin and high-strength fiber periodontal splints in repairing periodontitis with loss of teeth
ZHANG Lei, LIU Yi, LI Guomin, CHEN Chunhui, LI Xiaofang
2021, 19(8): 1273-1276. doi: 10.16766/j.cnki.issn.1674-4152.002038
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Objective To explore the repair effect of resin splint and high-strength fiber periodontal splint in patients with periodontitis and tooth loss, in order to improve the reference for the choice of clinical treatment. Methods Total 86 patients with periodontitis and missing teeth admitted to Jinhua C...
Analysis on risk factors of anastomotic leakage after anterior resection for rectal cancer
WANG Shuanhu, LIU Yakui, SHI Yi, GUAN Jiajia, LIU Mulin
2021, 19(8): 1277-1279. doi: 10.16766/j.cnki.issn.1674-4152.002039
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Objective With the application of total mesorectal excision (TME), the long-term effect of rectal cancer has been greatly improved. However, the incidence of postoperative anastomotic leakage of rectal cancer is not significantly reduced, so it is very important to explore the risk factors of postop...
Effect of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease
DING Cheng, MA Yuzhuo, HUANG Xingzhao, HUANG Jinping, ZHONG Liangjun, CHEN Xing
2021, 19(8): 1280-1282, 1299. doi: 10.16766/j.cnki.issn.1674-4152.002040
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Objective To evaluate the effects of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease (NAFLD). Methods Thirty moderate or severe periodontitis cases with NAFLD were selected from July 2018 to June 2019 in Department of Pe...
Effect of Ginkgo biloba extract on bFGF/Notch1 pathway in hippocampus of rats models with Alzheimer's disease
ZHAO Ping, LI Xin, CUI Jing, XIA Xiaoshuang, TIAN Wenjie
2021, 19(8): 1283-1286. doi: 10.16766/j.cnki.issn.1674-4152.002041
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Objective To explore the mechanism of Ginkgo biloba extract (GBE) in repairing AD rats' neurons related to Aβ25-35. Methods According to the random method, 60 rats meeting the requirements were divided into model group, normal control group, sham operation group, Ginkgo biloba experimental group (hi...
Correlation between ApoE genotype and carotid atherosclerosis and cerebral infarction
HUANG Liu, DAI Xinyu, TIAN Xue, YAO Jingqing, DAI Yue, LI Yunlao
2021, 19(8): 1287-1291. doi: 10.16766/j.cnki.issn.1674-4152.002042
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Objective To study the correlation between apolipoprotein E (ApoE) genotype and the stability and location of carotid atherosclerotic plaque and cerebral infarction. Methods Total 275 patients from the Second Affiliated Hospital of Nanjing Medical University from January 1, 2019 to December 31, 2019...
Expression of microRNA-1246 in the serum of hepatocellular carcinoma and its effect on biological function of HepG2 cells
WANG Pan, WANG Yichao, YU Dandan, CHEN Wenju, ZHONG Qianyi, TONG Binxin
2021, 19(8): 1292-1295,1313. doi: 10.16766/j.cnki.issn.1674-4152.002043
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Objective To investigate the expression of microRNA-1246 (miR-1246) in hepatocellular carcinoma (HCC) serum and its effect on the biological function of HepG2 cells. Methods Serum miR-1246 was determined by qRT-PCR in HCC patients and healthy controls. MiR-1246 mimics and NC mimics were transfected ...
General Clinical Research
Analysis of related factors of poor wound healing after closed lumbar fracture surgery
HAN Shuai, ZHAO Yu-peng, ZHOU Ping-hui, XIAO Yu-zhou
2021, 19(8): 1296-1299. doi: 10.16766/j.cnki.issn.1674-4152.002044
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Objective To investigate and analyse the related risk factors of poor incision healing after operation for lumbar closed fracture. Methods A total of 342 patients with closed lumbar fracture who were admitted to the department of orthopaedics in the First Affiliated Hospital of Bengbu Medical Colle...
Clinical study of thromboelastography in the diagnosis of traumatic coagulopathy after craniocerebral injury
ZHNAG Zhi-hua, YU Guo-feng
2021, 19(8): 1300-1302,1329. doi: 10.16766/j.cnki.issn.1674-4152.002045
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Objective To observe the clinical effect and prognostic value of thromboelastography (TEG) in the diagnosis of traumatic coagulopathy after craniocerebral injury. Methods Total 200 patients with acute craniocerebral injury in our hospital were selected as the research objects from December 2018 to F...
Clinical efficacy of dapagliflozin in the treatment of type 2 diabetes mellitus
SUN Wei, WANG Fei, YANG Guang-shu, YU Ying
2021, 19(8): 1303-1305. doi: 10.16766/j.cnki.issn.1674-4152.002046
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Objective To observe the clinical therapeutic effect, safety and tolerance of dapagliflozin combined with premix insulin in treatment for type 2 diabetes mellitus with poor glucose control. Methods Total 60 patients with type 2 diabetes mellitus with poor glycemic control treated with oral insulin a...
Observation of curative effect of bevacizumab combined with targeted treatment of EGFR mutant lung cancer
JIANG Yi-ling, ZHANG Chuan-ling, CHEN Cheng, YU Hong-jin, LI Wei-na, FANG Jing, FANG Yong
2021, 19(8): 1306-1309. doi: 10.16766/j.cnki.issn.1674-4152.002047
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Objective To investigate the effect of bevacizumab combined with targeted therapy on the short- and long-term prognosis, immune status, and side effects of patients with epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC), in order to provide reference for the choice of...
Effect of ultrasound-guided iliac fascia nerve block on hemodynamics and stress response in elderly patients with proximal femoral fracture
ZHU Jian-guo, ZHANG You-chuan, FENG Yi-cheng, ZHU Jun-jian, ZHAN Lin-sen
2021, 19(8): 1310-1313. doi: 10.16766/j.cnki.issn.1674-4152.002048
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Objective To analyze the application of ultrasound-guided iliac fascia nerve block in the anesthesia of elderly patients with proximal femoral fracture and its effect on hemodynamics and stress response. Methods Eighty-two cases of elderly patients with proximal femoral fracture in our hospital from...

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