中华全科医学

Quantitative research on general practitioner policies in China based on a three-dimensional analysis framework on a three-dimensional analysis framework

QI Li, WU Shuang, BAI Hairong, SUN Yu

2023, 21(11): 1813-1817. doi: 10.16766/j.cnki.issn.1674-4152.003231

360 26

Abstract:
Objective To analyze the text of China' s general practitioner training policy, explore the problems in the policy, and provide references and suggestions for the policy improvement. Methods Retrieve policy documents related to the general practitioner cultivation from the websites of the State Coun...

Analysis of influencing factors of vertebroplasty in the treatment of senile vertebral compression fracture

XU Fei, DOU Qiangbing, LI Xingxing, ZHENG Quan, WANG Qiwei, SUN Liangye

2023, 21(11): 1818-1822. doi: 10.16766/j.cnki.issn.1674-4152.003232

310 31

Abstract:
Objective To analyze the factors affecting the effect of vertebroplasty on senile vertebral compression fracture, in order to estimate the postoperative efficacy of patients and intervene in advance if necessary to improve the effectiveness of treatment. Methods A retrospective study was conducted o...

Efficacy of percutaneous unilateral balloon kyphoplasty combined with small-needle knife in the treatment of postoperative pain from single-level osteoporotic thoracolumbar vertebral compression fractures

ZHOU Wenjing, LI Huajie, SUN Huan, MIN Youbao, LIU Lei, ZHOU Pinghui

2023, 21(11): 1823-1826. doi: 10.16766/j.cnki.issn.1674-4152.0033233

308 18

Abstract:
Objective To evaluate the clinical efficacy of percutaneous unilateral balloon kyphoplasty combined with small-needle knife treatment in the management of postoperative pain in patients with single-level osteoporotic thoracolumbar compression fractures. Methods A total of 46 patients with single-lev...

GE Yu, YU Haiyang, LIANG Chengmin, ZHAI Yunlei, CUI Xilong, ZHENG Guohui, JIANG Jishi

2023, 21(11): 1827-1829, 1927. doi: 10.16766/j.cnki.issn.1674-4152.003234

245 17

Abstract:
Objective To investigate the relevant factors influencing the improvement of local kyphotic deformity in individuals afflicted with osteoporotic vertebral compression fractures (OVCF) following percutaneous kyphoplasty (PKP) combined with positional reduction intervention. Methods The data of OVCF p...

Application of quantitative goal exercise combined with whole process refined nutrition management in patients with hematological disease chemotherapy

ZHU Li, TANG Hailong, HU Lei, ZHAO Yinli, GUO Sijin

2023, 21(11): 1830-1833. doi: 10.16766/j.cnki.issn.1674-4152.003235

229 12

Abstract:
Objective To explore the effect of quantitative targeted exercise (QGE) combined with whole process refined nutrition management (WP-RNM) on the clinical results of patients with hematologic diseases undergoing chemotherapy, and to provide evidence for improving the quality of rehabilitation managem...

Efficacy of sildenafil citrate in treating pulmonary hypertension associated with connective tissue disease

LI Xueling, WANG Luyao, ZUO Zhengcai, WANG Guihong

2023, 21(11): 1834-1836. doi: 10.16766/j.cnki.issn.1674-4152.003236

280 14

Abstract:
Objective To investigate the changes of hemodynamic parameters and exercise ability in patients with pulmonary hypertension associated with connective tissue disease (CTD-PAH) before and after oral sildenafil citrate treatment, in order to evaluate its clinical efficacy. Methods Twenty-six CTD-PAH p...

Evaluation of the agreement between the anaerobic threshold and heart rate reserve methods of target exercise heart rate in a population with coronary artery disease

HAN Ling, LIU Qiang, LIU Yefa, FAN Xiaomian, XU Di, HOU Yonghong, WANG Dongwei, DING Rongjing

2023, 21(11): 1837-1840. doi: 10.16766/j.cnki.issn.1674-4152.003237

271 13

Abstract:
Objective To compare the anaerobic threshold target heart rate obtained from cardiopulmonary exercise test (CPET) with the target heart rate obtained from the heart rate reserve method to test the consistency of target heart rates obtained from different methods and to guide the formulation of exerc...

Pharmacokinetic study of single-dose fosaprepitant dimeglumine (150 mg) in healthy Chinese volunteers

LI Hongtao, HE Cuixia, ZHOU Huan, WANG Huaxue

2023, 21(11): 1841-1844. doi: 10.16766/j.cnki.issn.1674-4152.003238

223 9

Abstract:
Objective To study the time course of blood concentration after single-dose intravenous infusion of fosaprepitant dimeglumine for injection manufactured by Jiangsu Aosaikang Pharmaceutical Co., Ltd. in healthy Chinese subjects and to estimate the corresponding pharmacokinetic parameters. To evaluate...

Correlation between inflammatory response and peripheral blood platelet-lymphocyte ratio and vitelliform degeneration in human carotid atherosclerotic plaques

XING Benyuan, DAI Xinyu, DING Hong, NIAN Fujia, PENG Gang, LI Yuntao

2023, 21(11): 1845-1848. doi: 10.16766/j.cnki.issn.1674-4152.003239

378 17

Abstract:
Objective To investigate the correlation between inflammatory response and peripheral blood platelet-lymphocyte ratio (PLR) and vitreous degeneration in human carotid atherosclerotic plaques, and to provide a new basis for further diagnosis and treatment of atherosclerosis. Methods Thirty-nine patie...

Expression and significance of peripheral blood lymphocyte subsets in non-small cell lung cancer

ZHAO Hao, QI Xueyuan, WANG Junbin, ZHANG Xiaofeng, TAO Lu, YU Liang

2023, 21(11): 1849-1851. doi: 10.16766/j.cnki.issn.1674-4152.003240

365 21

Abstract:
Objective To investigate the dynamic changes and significance of lymphocyte subsets in peripheral blood of non-small cell lung cancer (NSCLC) patients with different pathological types and clinical stages, and to compare the immune status of non-small cell lung cancer patients with healthy people. M...

Antimicrobial resistance of common pathogens and their special types in urinary tract infection

ZHENG Siqiang, LIU Lin, FAN Shendong, SUN Wenbo, CHEN Bin, HE Qiang

2023, 21(11): 1852-1855. doi: 10.16766/j.cnki.issn.1674-4152.003241

301 24

Abstract:
Objective To investigate the antimicrobial resistance of common pathogenic bacteria and their special types in urine culture of urinary tract infection (UTI) patients, and to provide reference for clinical workers in the empirical treatment of urinary tract infection. Methods The urine culture resul...

Expression levels of serum Krebs von den Lungen-6 and interleukin 33 in rheumatoid arthritis patients and their clinical significance

HUANG Yue, WEI Xiaosong, JIANG Chao, WU Hanxia, WANG Tao, LI Zhijun

2023, 21(11): 1856-1859. doi: 10.16766/j.cnki.issn.1674-4152.003242

262 20

Abstract:
Objective To understand the expression levels of serum Krebs von den Lungen-6 (KL-6) and interleukin 33 (IL-33) in patients with rheumatoid arthritis (RA), and to investigate the diagnostic value of detecting serum KL-6 and IL-33 in RA-associated interstitial lung disease (RA-ILD). Methods A total o...

Establishment and validation of model for the risk of Carbapenem-Resistant Enterobacteriaceae infection in elderly patients with pulmonary infection

ZHAO Shiqi, WANG Shu, ZHANG Ying, WANG Shasha, TANG Wenjuan, LI Jing, ZHANG Xuemin, LI Fang

2023, 21(11): 1860-1864. doi: 10.16766/j.cnki.issn.1674-4152.003243

302 20

Abstract:
Objective To analyze and screen the high-risk factors for CRE infection in elderly people with pulmonary infection, and to construction and validate a risk nomogram prediction model. Methods Clinical data of a total of 894 elderly (≥60 years old) hospitalized patients with pulmonary infection cultur...

Effects of alfentanil on traction pain and shivering during combined spina-epidural anesthesial for cesarean section

GAO Zongbin, YANG Guang, SHI Zhou, HU Jun, WANG Ping

2023, 21(11): 1865-1867. doi: 10.16766/j.cnki.issn.1674-4152.003244

234 7

Abstract:
Objective To investigate the effect of alfentanil on the prevention of traction pain and shivering in puerperae during combined spina/epidural anesthesia (CSEA) cesarean section, to provide a reference for clinical work. Methods A total of 62 parturients who underwent cesarean section under combined...

Study on the effect of ultrasound-guided stellate ganglion block for preventing cognitive impairment after hip fracture surgery in the elderly

WANG Binhong, QIN Jinling

2023, 21(11): 1868-1871. doi: 10.16766/j.cnki.issn.1674-4152.003245

250 15

Abstract:
Objective Elderly patients have a higher risk of postoperative cognitive dysfunction (POCD), and this study investigates the improvement effect of ultrasound-guided stellate ganglion block (SGB) on cognitive function after hip fracture surgery in the elderly in order to improve the patient's prognos...

Evaluation of the association between disease perception and medication adherence in patients with drug-resistant pulmonary tuberculosis using the propensity score method

ZHENG Zhenhui, JIANG Qiaomin, ZHANG Zunjing

2023, 21(11): 1872-1875. doi: 10.16766/j.cnki.issn.1674-4152.003246

278 18

Abstract:
Objective The issue of medication adherence in patients with multi drug-resistance tuberculosis (MDR-TB) has received much attention. This study used propensity score matching (PSM) to explore the relationship between disease perception and medication adherence. Methods From June 2019 to October 202...

The effect of Shexiang Baoxin Pills combined with recombinant human brain natriuretic peptide in the treatment of ischemic heart failure

XIA Yi, LI Xuelong, QIAO Fengjie, DONG Wenbin

2023, 21(11): 1876-1879. doi: 10.16766/j.cnki.issn.1674-4152.003247

246 12

Abstract:
Objective To explore the clinical efficacy of Shexiang Baoxin pills combined with recombinant human brain natriuretic peptide in the treatment of ischemic heart failure, in order to provide reference for the treatment of ischemic heart failure patients. Methods A total of 100 patients with ischemic ...

Construction of a driving factor model of hypertension among physical examination middle-aged and elderly people in a top three hospital in Jiaxing City

DI Junjun, SHEN Liang

2023, 21(11): 1880-1883. doi: 10.16766/j.cnki.issn.1674-4152.003248

212 12

Abstract:
Objective To investigate the prevalence of hypertension among middle-aged and elderly people in a Level A Tertiary Hospital in Jiaxing City and to build a driving factor model for the development of preventive measures. Methods A total of 5 155 middle-aged and elderly people who underwent a physical...

Retrospective analysis of comorbidities and distribution differences in 511 patients with rheumatoid arthritis

WANG Qingsong, CAO Yunxiang, XU Yu, ZHANG Jinshan, RUAN Liping, WANG Rui

2023, 21(11): 1884-1887. doi: 10.16766/j.cnki.issn.1674-4152.003249

239 13

Abstract:
Objective To investigate the comorbidities of patients with rheumatoid arthritis (RA) and their distribution differences in different age, gender and course of disease, and to provide reference for better comprehensive prevention and treatment of RA and comorbidities. Methods Retrospective analysis ...

Clinical Observe of on maternal participation in kangaroo care during non-invasive ventilation therapy for low birth weight premature infants with RDS

ZHOU Peiyan, LUO Feixiang

2023, 21(11): 1888-1890. doi: 10.16766/j.cnki.issn.1674-4152.003250

197 10

Abstract:
Objective Low weight premature infants have a higher risk of developing respiratory distress syndrome (RDS), and the scientific and reasonable care methods directly affect the prognosis of the children. Therefore, the clinical effect of implementing mother' s participation in kangaroo care (KMC) dur...

Analysis of psychological factors and intervention of women with abnormal fetal induction of labor

HE Yan, YU Xiaoyan, YU Youfen, AN Jingna

2023, 21(11): 1891-1893. doi: 10.16766/j.cnki.issn.1674-4152.003251

285 10

Abstract:
Objective Abnormal fetal induction of labor not only causes damage to the mother' s physiology, but also causes great psychological trauma. The purpose of this study is to explore the factors analysis of maternal depression and anxiety caused by abnormal fetal labor induction, and to study the clini...

Observation study of the therapeutic effect of sacral nerve magnetic stimulation combined with pelvic floor muscle rehabilitation training on chronic pelvic pain in women

ZHOU Xiaohong, ZHANG Lin, SU Aifang

2023, 21(11): 1894-1897. doi: 10.16766/j.cnki.issn.1674-4152.003252

283 14

Abstract:
Objective The use of sacral nerve intervention targets in chronic pelvic pain (CPP) has received much attention. This study aims to investigate the effectiveness of sacral nerve magnetic stimulation combined with pelvic floor muscle rehabilitation training in the treatment of female CPP. Methods A t...

Research on the quality of life in patients with stable coronary artery disease under standardized management in community

YANG Ling, DU Xueping

2023, 21(11): 1898-1902. doi: 10.16766/j.cnki.issn.1674-4152.003253

268 15

Abstract:
Objective To analyze the difference of the quality of life of patients with stable coronary artery disease with different demographic characteristics and different behavior characteristics under standardized management in community, and put forward targeted measures to improve their quality of life....

Analysis of the current situation of demand for community home medical care with pension services and its influencing factors for the urban elderly

FU Youxing, CHENG Xia, LIU Jiayang, LIN Lin

2023, 21(11): 1903-1906. doi: 10.16766/j.cnki.issn.1674-4152.003254

535 28

Abstract:
Objective To investigate the current situation of the demand for community home medical care with pension services for the elderly in Chengdu, and to explore the influencing factors of the elderly' s choice of elderly care services, in order to provide reference for the construction of a demand-orie...

Social participation status and its related factors in patients with mild to moderate Parkinson's disease: a 275-case study

WANG Hong, XU Fanglei, TANG Ailing, ZHANG Yue, GUAN Qiang, GONG Haiyan

2023, 21(11): 1907-1911. doi: 10.16766/j.cnki.issn.1674-4152.003255

276 13

Abstract:
Objective To investigate the social participation status of people with mild to moderate Parkinson's disease (PD), and to analyze the factors associated with it, in order to provide a reference for intervention. Methods A total of 275 patients with mild to moderate PD who visited the clinic of the D...

Applied research of acceptance and commitment therapy in women with termination of pregnancy for fetal abnormality

TAO Lei, ZHANG Fengying, ZHOU Lihua, CHEN Jiayun, KUANG Ling, YANG Wenling

2023, 21(11): 1912-1915. doi: 10.16766/j.cnki.issn.1674-4152.003256

253 19

Abstract:
Objective To investigate the effectiveness of acceptance and commitment therapy (ACT) in women who have had an abortion because of a fetal abnormality. Methods A total of 139 eligible participants were recruited from a tertiary A hospital in Anhui province, China, and were divided into two groups ba...

Correlation analysis between maternal postpartum depression and early motor development in high-risk infants

WANG Lijuan, WANG Hui, TONG Lian, WANG Jun, ZHANG Yaping, HAN Qian, WANG Yueying, ZHANG Qing

2023, 21(11): 1916-1919. doi: 10.16766/j.cnki.issn.1674-4152.003257

221 10

Abstract:
Objective To explore the influence of maternal postpartum depression on early motor development of high-risk infants, and put forward health care measurements for high-risk infants from the perspective of mothers, with a result of improving early intervention, health management programs for enhancin...

Application of contrast-enhanced ultrasound precise puncture in transrectal prostate biopsy

HE Jia, LIU Ning, YU Tianqiang, SHI Kaiyuan, DUAN Yue

2023, 21(11): 1920-1923. doi: 10.16766/j.cnki.issn.1674-4152.003258

242 10

Abstract:
Objective To study the application effect of contrast-enhanced ultrasound precise puncture in transrectal prostate biopsy, aiming to improve the puncture positive rate, reduce patient pain, and provide a basis for clinical diagnosis and treatment. Methods A total of 150 patients with elevated prosta...

Clinical value of HE4 as a molecular marker for renal fibrosis

LI Hong, LI Geng, LIU Xing, YU Hong

2023, 21(11): 1924-1927. doi: 10.16766/j.cnki.issn.1674-4152.003259

315 11

Abstract:
Objective To investigate the changes of serum human epididymis protein 4(HE4) in patients with chronic kidney disease (CKD) and its diagnostic value for renal fibrosis. Methods A total of 159 patients with CKD who were treated in Wuhan Hospital of Traditional Chinese Medicine from January 2020 to Ja...

Research on the evaluation index of emergency response capacity of major pandemic

WANG Jiaxin, WU Hao, ZHAO Jingwei, ZHAO Yali

2023, 21(11): 1928-1931. doi: 10.16766/j.cnki.issn.1674-4152.003260

338 21

Abstract:
Emergency management system and capacity are important parts of national governance systems and capacities. The construction of public health emergency management system is the key factor to deal with public health emergencies. In the context of the COVID-19, it is of great significance to improve h...

Research progress on molecular biological characteristics of IgG subclasses and its clinical application in related diseases

ZHANG Sheng, CAO Jun, JIN Jieyu, LIANG Yuting

2023, 21(11): 1932-1935. doi: 10.16766/j.cnki.issn.1674-4152.003261

873 50

Abstract:
Immunoglobulin (Ig) is a glycoprotein secreted by the adaptive immune system, which plays an important role in humoral immunity, including immunoglobulin G (IgG), immunoglobulin M (IgM), immunoglobulin A (IgA), immunoglobulin E (IgE), and immunoglobulin D (IgD). Among them, IgG is the main component...

Evaluation and management of tall stature in children

MU Jialin, CHEN Zhihong

2023, 21(11): 1936-1940. doi: 10.16766/j.cnki.issn.1674-4152.003262

305 26

Abstract:
Tall stature is defined as a height more than two standard deviations (SD) above the mean for the same race, age and sex; or greater than the 97th percentile. It is also defined as the height exceeds the midparental height by more than 2 SD. There has been a high degree of acceptance for tall statur...

Observation on the curative effect of Baihui penetrating Qubin acupuncture combined with suspension therapy in the treatment of complex regional pain syndrome type Ⅰ after stroke

WANG Jing, WANG Ruiping, XUE Yang, SONG Yujin, GU Yujing, ZHU Lin

2023, 21(11): 1941-1945. doi: 10.16766/j.cnki.issn.1674-4152.003263

270 8

Abstract:
Objective To observe the effects of Baihui penetrating Qubin acupuncture combined with suspension therapy on pain, upper limb function, shoulder joint movement, hand swelling, and activities of daily living in patients with complex regional pain syndrome type Ⅰ (CRPS-Ⅰ) after stroke. Methods A total...

Application of rehabilitation training based on information-motivation-behavioral skills model in postpartum pelvic floor muscle repair

HU Lingbo, PAN Chengyao, YANG Sujuan, MA Binbin, WANG Rongyue

2023, 21(11): 1946-1950. doi: 10.16766/j.cnki.issn.1674-4152.003264

311 12

Abstract:
Objective To explore the effect of rehabilitation training intervention based on the information-motivation-behavioral skills model on the repair of pelvic floor function in parturients. Methods One hundred and thirty-five women who underwent pelvic floor muscle screening at 42 d postpartum and diag...

Analysis of the first national outpatient teaching competition for general practitioners in Sichuan Province

LIANG Lingbo, SHI Yi, LU Wenting, BI Mingshua, ZENG Yongqiu, SU Qiaoli

2023, 21(11): 1951-1953. doi: 10.16766/j.cnki.issn.1674-4152.003265

275 9

Abstract:
Objective To improve the outpatient teaching skills of general practitioners, the Chinese Medical Doctor Association organized the first national outpatient teaching competition to standardize the training of general practitioner residents. This study analyzed the competition and self-assessment res...

Study on effect of PRECEDE-PROCEED model on improving diabetes management ability of internship nursing students

CHEN Na, SHI Guanhua, YANG Lijuan, LEI Tingting, ZHOU Jing, CHEN Yongxia

2023, 21(11): 1954-1957. doi: 10.16766/j.cnki.issn.1674-4152.003266

283 10

Abstract:
Objective To explore the effects of diabetes management education project based on PRECEDE-PROCEED model on improving the diabetes management ability of internship nursing students. Methods Convenience sampling was used to select 180 internship nursing students who practiced in a hospital as the res...

An example of medical molecular biology course based on curriculum ideology and politics

WANG Yajuan, CHENG Yuanfang, YANG Quanzhong, WANG Xiaoyin

2023, 21(11): 1958-1962. doi: 10.16766/j.cnki.issn.1674-4152.003267

298 16

Abstract:
The integration of ideological and political education into the curriculum of professional courses is a key focus of current curriculum reform. In the training of medical students, while imparting medical knowledge, attention should also be paid to their ideological and political education, integrat...

Analysis of health literacy status and related factors in patients with chronic atrophic gastritis

SU Bochao, FENG Bojunhao, LI Yunshan, SUO Baojun, WU Yibo, ZHANG Jintai

2023, 21(11): 1963-1966. doi: 10.16766/j.cnki.issn.1674-4152.003268

283 12

Abstract:
Objective To explore the status and influencing factors of health literacy in patients with chronic atrophic gastritis and to provide suggestions for health education for patients with chronic atrophic gastritis. Methods Investigators were recruited to distribute and collect questionnaires in the wa...

Analysis of FN1, COL4A1, COL4A2 genes expression and significance in gastric cancer based on database mining

LEI Xinyi, SONG Danjun, DAI Gaiguo, ZHANG Yunli, YANG Litao

2023, 21(11): 1967-1971. doi: 10.16766/j.cnki.issn.1674-4152.003269

294 16

Abstract:
Objective To identify the potential hub genes for the prognosis and targeted therapy of stomach cancer. Methods GSE33651 and GSE118916 datasets were selected from gene expression omnibus (GEO, study periods were from November 2011 to August 2019). The differentially expressed genes (DEGs) were ident...

Study on nursing care of schizophrenia patients with diabetes by individualized intervention based on recovery concept

LIN Ling, ZHANG Yi, HE Mei

2023, 21(11): 1972-1976. doi: 10.16766/j.cnki.issn.1674-4152.003270

296 14

Abstract:
Objective The nursing of schizophrenia complicated with diabetes should be paid more attention. This study discusses the application effect of individualized nursing intervention based on the concept of rehabilitation. Methods A total of 122 patients with schizophrenia combined with diabetes admitte...

Application effect of a continuous nursing care centered on timing theory in patients with depression

CHEN Xinxia, ZHOU Suming, DONG Qifang, FENG Hong

2023, 21(11): 1977-1981. doi: 10.16766/j.cnki.issn.1674-4152.003271

336 16

Abstract:
Objective To analyze the application effect of the continuity nursing model based on timing theory in patients with depression. To explore its influence on patients' depressive symptoms, self-efficacy, quality of life and medication compliance, and to provide new ideas for clinical nursing. Methods ...

Invasive Klebsiella pneumoniae liver abscess syndrome in type 2 diabetes mellitus: a case report and literature review

ZHU Xinlin, ZHANG Lin, ZENG Zhengyan, WU Yanan, LI Canhui

2023, 21(11): 1982-1986. doi: 10.16766/j.cnki.issn.1674-4152.003272

380 29

Abstract:
In recent years, invasive Klebsiella pneumoniae liver abscess syndrome (IKLAS) has gradually developed in type 2 diabetes mellitus (T2DM). Due to its hidden symptoms, high virulence and susceptibility to metastatic infection, it is particularly difficult to manage such cases in the clinic. The diagn...

A case of type Ⅰ Kounis syndrome caused by drug allergy

YANG Changlin, CAO Shufeng, QIAO Lian, ZHAO Huimin

2023, 21(11): 1987-1989. doi: 10.16766/j.cnki.issn.1674-4152.003273

225 15

Abstract:
Kounis syndrome is a syndrome of coronary artery spasm and even acute myocardial infarction secondary to anaphylaxis. The elderly patient in this case developed delayed anaphylaxis when using piperacillin sodium and tazobactam sodium for anti-infective treatment of community-acquired pneumonia in ho...

Severe tsutsugamushi disease complicated with severe pneumonia, ncephalitis and multiple organ dysfunction: a case report

XIE Xiuyin, WANG Kuliang, XIE Youling, WEI Qingfei

2023, 21(11): 1990-1994. doi: 10.16766/j.cnki.issn.1674-4152.003274

291 9

Abstract:
Scrub typhus is an acute natural infectious disease caused by infection with Orientia tsutsugamushi, one of the most easily overlooked infectious diseases today. It is characterized by sudden onset with high fever, skin eschar or ulcer and lymph node enlargement. The basic pathological changes are v...

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2023 Vol. 21, No. 11

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