中华全科医学

Research and predictive analysis on the fairness of resource allocation of general practitioners in China

WU Shuang, SUN Yu, QI Li, CAO Zhihui

2024, 22(11): 1813-1817. doi: 10.16766/j.cnki.issn.1674-4152.003740

128 9

Abstract:
Objective To analyze the equity of general practitioner allocation in China and to forecast future trends. The findings will provide a theoretical reference for the promotion of general practice development. Methods The research sample comprised the number of general practitioners in China from 2017...

Progress in research on peripheral blood cytokines for evaluating efficacy after TACE in primary liver cancer

WANG Lin, YANG Xiaoli, YAN Yuling

2024, 22(11): 1818-1821. doi: 10.16766/j.cnki.issn.1674-4152.003741

106 5

Abstract:
Primary liver cancer ranks among the most prevalent and deadly malignancies globally, making timely and effective treatment, along with precise efficacy assessment, crucial for improving patient survival rates. Transarterial chemoembolization (TACE) is a vital treatment for intermediate and advanced...

Comprehensive analysis of the prognostic and immunological significance of EXO1 in hepatocellular carcinoma

YU Jinhui, WANG Wei, LYU Zhenyu, JI Wenbin, YU Huihao, YANG Yan

2024, 22(11): 1822-1826. doi: 10.16766/j.cnki.issn.1674-4152.003742

98 4

Abstract:
Objective To analyze the expression of exonuclease 1 (EXO1) in hepatocellular carcinoma (HCC) and to investigate the relationship between EXO1 and prognosis and immune cell infiltration in patients with HCC. Methods The expression of EXO1 in HCC and normal tissues was analyzed based on The Cancer Ge...

A two-center study of MRI and clinical parameter-based nomogram for predicting the efficacy of D-TACE in hepatocellular carcinoma

WANG Jieyu, XI Zihan, TIAN Yuchi, YANG Yongbo, QIU Huafeng, ZENG Hui, LIANG Xiaoyun, JIANG Haitao

2024, 22(11): 1827-1832. doi: 10.16766/j.cnki.issn.1674-4152.003743

102 2

Abstract:
Objective To investigate the effects of preoperative imaging features on baseline contrast-enhanced MRI, as well as clinically relevant factors on the efficacy of drug-eluting bead transarterial chemoembolization (D-TACE). Methods A retrospective analysis of patients from two centers who received D-...

Study of the relationship between serum sCD14, HMGB1 levels and cross-infection in orthodontic patients

FANG Min, ZOU Ying, CHENG Chun, WANG Qing, MI Congbo

2024, 22(11): 1833-1836. doi: 10.16766/j.cnki.issn.1674-4152.003744

112 4

Abstract:
Objective To investigate the relationship between serum soluble cluster of differentiation antigen 14 (sCD14) and high mobility group B1 (HMGB1) levels and the occurrence of cross-infection in orthodontic patients, as well as their predictive value for cross-infection. Methods A total of 183 orthodo...

Embryonic development and clinical outcomes in patients with 0PN zygote derived embryos

FAN Yongqi, YANG Dandan, ZHANG Qiqi, YAN Bo, ZHANG Zhiguo

2024, 22(11): 1837-1841. doi: 10.16766/j.cnki.issn.1674-4152.003745

64 1

Abstract:
Objective The cause of abnormal fertilization and embryo development in non-pronucleus (0PN) zygotes remains unclear, and the viability of transferring 0PN zygotes is still controversial. The study aims to explore the clinical utility of 0PN zygote-derived embryos. Methods A total of 9 167 IVF/ICSI ...

The expression and clinical significance of PTEN and miR-215 in retinoblastoma

WU Kangping, HUANG Jing, WANG Lina, YE Bei, ZHU Yanan

2024, 22(11): 1842-1845. doi: 10.16766/j.cnki.issn.1674-4152.003746

90 3

Abstract:
Objective Retinoblastoma (RB) can impair the vision and threaten the lives of children. The purpose of this study is to provide guidance for individualized treatment and prognosis assessment of children by investigating the expression and clinical significance of phosphatase and tensin homolog delet...

Application of end-to-side arterial anastomosis in transplantations of medial sural artery perforator flap

QIU Haisheng, NI Xiao, YU Fangzheng, ZHANG Lei

2024, 22(11): 1846-1849. doi: 10.16766/j.cnki.issn.1674-4152.003747

101 1

Abstract:
Objective To explore the clinical efficacy of free medial sural artery perforator flap transplantation for repairing soft tissue defects in the hands and feet. Methods In the Department of Hand Surgery at the First Affiliated Hospital of Wenzhou Medical University from March 2015 to July 2023, we us...

Analysis of risk factors for orthostatic hypotension in the elderly

HUO Chuning, LI Guanfei, LI Song

2024, 22(11): 1850-1853. doi: 10.16766/j.cnki.issn.1674-4152.003748

127 4

Abstract:
Objective To explore the prevalence rate and risk factors of orthostatic hypotension (OH) in the elderly, and to provide scientific basis for optimizing blood pressure adjustment measures in elderly OH patients. Methods Medical history collection, systolic and diastolic blood pressure and heart rate...

Research on the regulation of malignant biological behavior of colon cancer cells by Hsa miR-654-5p and its clinical significance

WANG Haiquan, LI Zhaohui, SUN Shengan, WANG Yunshuai, SHI Shousen

2024, 22(11): 1854-1858. doi: 10.16766/j.cnki.issn.1674-4152.003749

109 2

Abstract:
Objective Detect the expression of Hsa-miR-654-5p in colon cancer, analyze its impact on the malignant biological behavior of colon cancer cells and its clinical significance. Methods Detect the expression of Hsa-miR-654-5p in colon cancer cells (HT-29, Caco-2, SW480, HCT116, LOVO) and human normal ...

A study on the relationship between intracardiac hyperechogenic focus and chromosomal abnormality and prognosis

WANG Di, WANG Jing

2024, 22(11): 1859-1862. doi: 10.16766/j.cnki.issn.1674-4152.003750

104 2

Abstract:
Objective To investigate the degree of association between intracardiac hyperechogenic focus (ICEF) and genetic chromosomal abnormalities, and to discuss the implications of assessing fetal prognosis. Methods A retrospective study design was used to analyze 450 cases of intracardiac hyperechogenic f...

The expression of GZMB and PD-L1 and their relationship with prognosis in non-small cell lung patients

SUN Aolong, ZHANG Like, XU Quanxiao, WEN Xin, LI Weiyang

2024, 22(11): 1863-1867. doi: 10.16766/j.cnki.issn.1674-4152.003751

118 2

Abstract:
Objective To analyze the expression and clinical significance of granzyme B (GZMB) and programmed cell death ligand 1 (PD-L1) in non-small cell lung cancer (NSCLC). Methods Tumor and tumor-adjacent tissues were collected in 105 NSCLC patients from January 2015 to December 2019, and the expressions o...

Clinical efficacy of single hole split endoscopy assisted by ultrasound bone knife in the treatment of calcified lumbar disc herniation

TAN Fang, ZHANG Yan, ZHANG Feng, HU Peng, WANG Mingfei, HAN Shuai, SONG Xin, YU Tao, WANG Jian

2024, 22(11): 1868-1871. doi: 10.16766/j.cnki.issn.1674-4152.003752

81 2

Abstract:
Objective To examine the clinical efficacy of ultrasonic osteotome-assisted one-hole split endoscopic discectomy (OSED) for calcified lumbar disc herniation (CLDH) and to provide a clinical reference point. Methods A retrospective analysis was conducted on 25 patients with CLDH who were treated at t...

Efficacy of donepezil combined with cognitive rehabilitation in treating Alzheimer's disease based on near-infrared brain function detection

ZHANG Lie, LING Yingchun, GAO Gangmei

2024, 22(11): 1872-1875. doi: 10.16766/j.cnki.issn.1674-4152.003753

93 2

Abstract:
Objective To investigate the influence of donepezil combined with cognitive rehabilitation on cognitive function, daily living ability, and oxidative stress level of Alzheimer's disease (AD), and explore the efficacy based on near-infrared brain function detection of prefrontal lobe hemoglobin (HbO)...

Correlation analysis between serum iron-related indicators and risk of post-stroke cognitive impairment in stroke patients

CHEN Juan, CHEN Shixuan, WANG Feng, HUANG Wenwen

2024, 22(11): 1876-1879. doi: 10.16766/j.cnki.issn.1674-4152.003754

113 1

Abstract:
Objective To explore the correlation between serum iron (SI) related indexes and the risk of post-stroke cognitive impairment (PSCI), providing a theoretical basis for clinical intervention in PSCI. Methods A retrospective analysis was conducted on the clinical data of 281 stroke patients treated at...

LASSO regression to identify predictors and model construction for postoperative residual pain in patients with osteoporotic vertebral compression fracture

SHU Cunhong, ZHANG Yaoping, ZHANG Yuanbin

2024, 22(11): 1880-1883. doi: 10.16766/j.cnki.issn.1674-4152.003755

110 3

Abstract:
Objective To investigate factors of residual pain following percutaneous vertebroplasty (PVP) in patients with osteoporotic vertebral compression fracture (OVCF) and to construct a Nomgram model based on LASSO regression for identifying relevant factors. This aims to provide reference for early iden...

The long-term improvement effect of high flux hemodialysis on cardiac function ultrasound index, serum myocardial injury and inflammatory biochemical index in elderly patients with diabetic nephropathy

YANG Jianxiang, LIN Yongqiang

2024, 22(11): 1884-1886. doi: 10.16766/j.cnki.issn.1674-4152.003756

99 4

Abstract:
Objective High-flux hemodialysis (HFHD) was performed in elderly patients with diabetic nephropathy (DN) maintenance hemodialysis (MHD) to evaluate the long-term improvement of cardiac function ultrasound index, serum myocardial injury, and inflammatory biochemical index. Methods A total of 93 elder...

Observation on the effect of Shen Yuanliang's prescription in treating CAG patients

XIAO Yong, JIN Shaowei, DONG Zhen, WANG Tianshu

2024, 22(11): 1887-1890. doi: 10.16766/j.cnki.issn.1674-4152.003757

119 1

Abstract:
Objective To explore the improvement effect and mechanism of Shen Yuanliang's prescription in treating chronic atrophic gastritis (CAG) on gastric mucosal lesions. Methods A total of 105 CAG patients admitted to Shaoxing Hospital of Traditional Chinese Medicine from September 2020 to September 2023 ...

Analysis of infant care service needs and associated factors in Chizhou City, Anhui Province

WEI Suo, LIN Tieliu, MAO Huifang, WANG Jun, CHENG Jin

2024, 22(11): 1891-1894. doi: 10.16766/j.cnki.issn.1674-4152.003758

84 3

Abstract:
Objective This study aims to analyze the demand for infant care services and the related family determinants in Chizhou, Anhui Province, to provide scientific guidance for developing effective intervention measures. Methods A self-designed questionnaire was utilized to 877 parents and pregnant women...

Expression of Sestrin2 in serum of neonatal hypoxic-ischemic encephalopathy and its correlation with disease severity

LI Mingzhu, WEN Ronghua, YUE Qing

2024, 22(11): 1895-1898. doi: 10.16766/j.cnki.issn.1674-4152.003759

61 4

Abstract:
Objective To investigate the expression of serum Sestrin2 in neonates with hypoxic ischemic encephalopathy (HIE) and its clinical significance in order to improve the diagnostic accuracy and prognosis of HIE. Methods A total of 78 HIE children admitted to Linfen People's Hospital from June 2020 to A...

Analysis of chronic disease management implementation in community health service center in Shanghai

ZHOU Yingda, JIN Hua, YU Hao, CHEN Chen, QIU Baohua, SHI Ling, YU Dehua

2024, 22(11): 1899-1903. doi: 10.16766/j.cnki.issn.1674-4152.003760

100 3

Abstract:
Objective To investigate the overall implementation of chronic disease management in community health centers in Shanghai, and to assess and improve the current status of chronic disease management in community health centers in Shanghai. Methods In July 2022, a total of 247 community health centers...

Survey on the mental health status and influencing factors of ICU nurses in the post epidemic era

LIU Jie, LI Lei, WANG Xiaocheng, ZHANG Nan

2024, 22(11): 1904-1907. doi: 10.16766/j.cnki.issn.1674-4152.003761

93 3

Abstract:
Objective To investigate the mental health status of ICU nurses and the factors affecting them in the post epidemic era. Methods A total of 300 nurses working in the ICU of a military hospital were investigated from November 2023 to December 2023, and questionnaires were administered using the socia...

Analysis of potential categories of mental health literacy in maintenance hemodialysis patients

WANG Ying, XU Hui, WENG Lina

2024, 22(11): 1908-1911. doi: 10.16766/j.cnki.issn.1674-4152.003762

112 3

Abstract:
Objective This paper aims to explore the potential categories of mental health literacy in maintenance hemodialysis patients and discuss the influencing factors of different potential profile categories. Methods A total of 255 patients undergoing maintenance hemodialysis, admitted to Hai' an Municip...

The effect of narrative nursing combined with aerobic resistance exercise on depression symptoms and coping strategies in adolescent depression patients

YANG Xiaoyan, CHEN Jing, ZHANG Huiling, XU Dongqin

2024, 22(11): 1912-1916. doi: 10.16766/j.cnki.issn.1674-4152.003763

111 4

Abstract:
Objective Depression and its adverse consequences have become the third reason for the death among youngsters depression. This study explores the impact of narrative nursing combined with aerobic resistance exercise on depression symptoms and coping strategies in adolescent depression patients, prov...

Application of uterine artery flow parameters combined with serum alpha-fetoprotein in predicting premature birth in twins

XING Lili, FAN Shuyu, YU Hongxia, CAO Ning

2024, 22(11): 1917-1920. doi: 10.16766/j.cnki.issn.1674-4152.003764

97 2

Abstract:
Objective Preterm birth (PTB) is the main cause of neonatal death. Twins at high risk of PTB are susceptible to placental barrier rupture and fetal blood flow entering the mother, resulting in an increase in maternal serum alpha-fetoprotein (AFP) levels. The purpose of this study was to explore the ...

Study on the clinical effect of three-dimensional amide proton transfer imaging and diffusion-weighted imaging for diagnosis and prognosis evaluation of cervical cancer

SHI Tianliang

2024, 22(11): 1921-1923. doi: 10.16766/j.cnki.issn.1674-4152.003765

75 2

Abstract:
Objective This study aims to explore the potential value of 3D amide proton transfer imaging (3D-APT) in the diagnosis and treatment of cervical cancer by comparing its differences in the qualitative diagnosis and prognostic evaluation of cervical tissue lesions with diffusion-weighted image (DWI). ...

Advances in endoscopic translaminar approach for lumbar interbody fusion

CHEN Chaobo, QIAN Shu, ZHAO Jingwei, HENG Wei, QIAN Jixian, ZHOU Chengpei

2024, 22(11): 1924-1928. doi: 10.16766/j.cnki.issn.1674-4152.003766

108 1

Abstract:
In recent years, the rapid development of spinal endoscopic techniques and minimally invasive instruments has significantly expanded the use of endoscopic technology in spinal surgery. From the initial simple nucleus pulposus removal for decompression, to the extended decompression of the spinal can...

Development and research progress in medical stapler: domestic and international perspectives

ZHOU Yang, WANG Tianying, GU Wei

2024, 22(11): 1929-1933. doi: 10.16766/j.cnki.issn.1674-4152.003767

97 1

Abstract:
This paper discusses the development of medical staplers both domestically and internationally, analyzing the introduction, promotion, technological progress, market changes, and regulatory status of staplers in China. It focuses on the performance of staplers in terms of technology, product types, ...

Developing clinical management strategies based on factors influencing perioperative hypothermia

LUO Yuanyuan, CHENG Fan, CAI Zhongxiang, NING Jinzhuo, YAO Weidong

2024, 22(11): 1934-1937. doi: 10.16766/j.cnki.issn.1674-4152.003768

169 5

Abstract:
Perioperative hypothermia (core temperature < 36 ℃) is a common complication in surgical patients, influenced by several patient-centered external factors such as medications, comorbidities, trauma, ambient temperature, type of anesthesia, and the extent and duration of the procedure. This articl...

Effect of Buyang Huanwu Decoction combined with individual cognitive training on post-stroke cognitive dysfunction and neurological function

WANG Guojun, LEI Haijun, YANG Li, JING Rong, GAO Li, FU Chun'ai

2024, 22(11): 1938-1941. doi: 10.16766/j.cnki.issn.1674-4152.003769

72 2

Abstract:
Objective To explore the effects of combing the classic formula Buyang Huanwu Decoction with personalized cognitive training on cognitive dysfunction and neurological function after stroke. Methods A total of 98 post stroke cognitive impairment (PSCI) patients were selected form those admitted to th...

Application of acupoint application after moxibustion and anal lifting exercise in urinary incontinence in elderly stroke patients

PENG Qingjie, SHI Yangyang, HONG Liang, YANG Yanfu

2024, 22(11): 1942-1944. doi: 10.16766/j.cnki.issn.1674-4152.003770

107 3

Abstract:
Objective The occurrence of urinary incontinence following a stroke has a significant impact on the daily lives of patients. This paper considers the potential benefits of acupuncture point application following moxibustion and anal lifting exercise in the management of urinary incontinence followin...

Observation on the effect of self-made Qinggan Mingmu Shengjin Runzao Tang ultrasonic atomization therapy on dry eye syndrome of liver and kidney yin deficiency type

ZHANG Guoying, DU Chengchun, GUAN Wenqing

2024, 22(11): 1945-1949. doi: 10.16766/j.cnki.issn.1674-4152.003771

98 2

Abstract:
Objective To explore the effect of self formulated Qinggan Mingmu Shengjin Runzao Tang ultrasonic atomization therapy on dry eye syndrome of liver and kidney yin deficiency type. Methods A total of 158 patients with liver and kidney-yin deficiency type dry eye syndrome admitted to our hospital from ...

Medical technical skills competition promotes practice application of traditional Chinese medicine in surgical teaching

CHEN Tingting, HUANG Fengjing, , ZHENG Chenguo

2024, 22(11): 1950-1952. doi: 10.16766/j.cnki.issn.1674-4152.003772

57 4

Abstract:
Objective This study aimed to reform the teaching of traditional Chinese medicine (TCM) by integrating the content and mode of medical technical skills competition, and to explore the effectiveness of promoting learning and teaching by competitions. Methods The five-year undergraduate class of TCM a...

Application effect of standardized patient combined with Leicester assessment package evaluation method in general outpatient teaching

JIN Mingwei, FAN Yijun, GUO Ming, BAI Yang, ZHAN Xuebin, LI Jimeng

2024, 22(11): 1953-1956. doi: 10.16766/j.cnki.issn.1674-4152.003773

101 4

Abstract:
Objective Exploring the application value of standardized patient (SP) combined with Leicester assessment package (LAP) in general outpatient teaching. Methods Thirty students who participated in the general assistant training program at the Seventh People' s Hospital of Zhengzhou from 2021 to 2022,...

Clinical efficacy and safety of Xiao' er Chaigui Tuire Granules in the treatment of acute upper respiratory tract infection: a meta-analysis

LI Yun, CHANG Wenjing, ZHANG Xudong, ZHANG Juwen, CHEN Wei

2024, 22(11): 1957-1962. doi: 10.16766/j.cnki.issn.1674-4152.003774

110 1

Abstract:
Objective To systematically evaluate the clinical efficacy and safety of Xiao' er Chaigui Tuire Granules alone or combined with Western medicine in the treatment of acute upper respiratory tract infection, and to provide evidence-based basis for clinical application. Methods The clinical literatures...

Constraint-induced movement combined therapy to promote the recovery of stroke patients: a network meta-analysis

WANG Aiyao, TIAN Jie, SUN Yaohuan, DING Xingxing, LIAN Shuying, JIANG Suting, DONG Yinfeng

2024, 22(11): 1963-1966. doi: 10.16766/j.cnki.issn.1674-4152.003775

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102 3

Abstract:
Objective To systematically review the efficacy of constraint-induced movement combined therapy on exercise ability and daily living in stroke patients. Methods We searched the Web of Science, PubMed, etc, a total of 8 databases to collect the clinical randomized controlled trials (RCTs) of (modifie...

Systematic analysis of the effect of intensive breathing training on the application of rehabilitation for patients with post-stroke dysphagia

WU Liyan, CUI Yanyin, ZHANG Yujie, LEI Shanyan, YANG Fang

2024, 22(11): 1967-1970. doi: 10.16766/j.cnki.issn.1674-4152.003776

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138 3

Abstract:
Objective To systematically evaluate the effect of intensive respiratory training on the rehabilitation application of dysphagia after stroke. Methods The controlled studies of intensive breathing training on rehabilitation of swallowing disorder after stroke from PubMed, Embase, Cochrane Library, W...

Research hotspot of moyamoya disease: a visualized analysis based on CiteSpace software

MA Yunyun, JIANG Zijuan, LI Ping, WANG Xiaoxiao, ZHANG Luoluo

2024, 22(11): 1971-1975. doi: 10.16766/j.cnki.issn.1674-4152.003777

81 2

Abstract:
Objective To search and visually analyze the literature related to moyamoya disease based on CiteSpace, and summarize the research status, research hotspot and development trend in this field, in order to provide reference for subsequent research. Methods The literature related to moyamoya disease i...

Development of a risk scoring tool for hospital-acquired pressure ulcer in gynecological surgery patients

LU Tingting, WANG Yan, ZHANG Yinghui

2024, 22(11): 1976-1980. doi: 10.16766/j.cnki.issn.1674-4152.003778

93 4

Abstract:
Objective This study aims to explore the risk factors for hospital-acquired pressure ulcers in patients undergoing gynecological surgery and to develop an effective prediction tool based on these factors. Methods Risk factors for pressure ulcers were identified through a literature review. Clinical ...

The effect of task-oriented family participation nursing model on patients and caregivers after esophageal cancer surgery

YAN Yanyan, TONG Yaping, CHEN Lijuan, CAI Shuping

2024, 22(11): 1981-1985. doi: 10.16766/j.cnki.issn.1674-4152.003779

110 3

Abstract:
Objective To investigate the effects of a task-oriented family engagement care model on self-care ability, caregiver caregiving ability, and patient prognosis in esophageal cancer surgery. Methods A convenient sampling method was used to select 78 esophageal cancer inpatients diagnosed with esophage...

Effect of early pelvic floor muscle exercises on urinary incontinence and quality of life after orthotopic ileal neobladder surgery

ZHANG Hongqin, LIU Beibei, WANG Fei, LU Yingli, LI Jian

2024, 22(11): 1986-1989. doi: 10.16766/j.cnki.issn.1674-4152.003780

87 3

Abstract:
Objective To study the effect of early pelvic floor muscle exercises on urinary incontinence and quality of life in patients undergoing orthotopic ileal neobladder surgery for bladder cancer. Methods Fifty-six patients with bladder cancer treated in the First Affiliated Hospital of Bengbu Medical Un...

Effect of continuous care with low FODMAP dietary guidance on nutritional status and intestinal flora in patients with ulcerative colitis

YANG Mei, TONG Jingfei, GAO Ying, YU Xueyao

2024, 22(11): 1990-1994. doi: 10.16766/j.cnki.issn.1674-4152.003781

98 2

Abstract:
Objective Constructing a continuous nursing program guided by a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet to help patients with ulcerative colitis improve their nutritional status, regulate intestinal flora, and optimize the quality of care. Methods A...

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2024 Vol. 22, No. 11

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